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Department of Clinical and Biological Sciences

Department of Clinical and Biological Sciences

Logo di Department of Clinical and Biological Sciences

Rachele Francese

(RTDa) Research Fellows

Contacts

At

  • Dipartimento di Scienze Cliniche e Biologiche
  • Corso di laurea in Infermieristica - sede Orbassano Polo Medicina Orbassano e Candiolo

Curriculum vitae

  • Curriculum Vitae (0.1 MB)

    • Selected research products

    Scopus ID: 57193061831

    1. Luceri A, Francese R, Perero S, Lembo D, Ferraris M, Balagna C. Antibacterial and Antiviral Activities of Silver Nanocluster/Silica Composite Coatings Deposited onto Air Filters. ACS Appl Mater Interfaces. 2024 Jan 9. doi: 10.1021/acsami.3c13843. Epub ahead of print. PMID: 38195426. (IF: 9.5, Q1)
    2. Francese R, Peila C, Donalisio M, Lamberti C, Cirrincione S, Colombi N, Tonetto P, Cavallarin L, Bertino E, Moro GE, Coscia A, Lembo D. Viruses and Human Milk: Transmission or Protection? Adv Nutr. 2023 Aug 20:S2161-8313(23)01357-1. doi: 10.1016/j.advnut.2023.08.007. Epub ahead of print. PMID: 37604306. (IF: 9.3, Q1)
    3. Maglione A*, Francese R*, Arduino I, Rosso R, Matta M, Rolla S, Lembo D, Clerico M. Long-lasting neutralizing antibodies and T cell response after the third dose of mRNA anti-SARS-CoV-2 vaccine in multiple sclerosis. Front Immunol. 2023 Jun 19;14:1205879. doi: 10.3389/fimmu.2023.1205879. PMID: 37409134; PMCID: PMC10318111. (IF: 7.3, Q1)
    4. Luceri A*, Francese R*, Lembo D, Ferraris M, Balagna C. Silver Nanoparticles: Review of Antiviral Properties, Mechanism of Action and Applications. 2023 Feb 28;11(3):629. doi: 10.3390/microorganisms11030629. PMID: 36985203; PMCID: PMC10056906. (IF: 4.926, Q2)
    5. Chen R*, Francese R*, Wang N, Li F, Sun X, Xu B, Liu J, Liu Z, Donalisio M, Lembo D, Zhou GC. Exploration of novel hexahydropyrrolo[1,2-e]imidazol-1-one derivatives as antiviral agents against ZIKV and USUV. Eur J Med Chem. 2023 Feb 15;248:115081. doi: 10.1016/j.ejmech.2022.115081. Epub 2023 Jan 3. PMID: 36623328. (IF: 7.088, Q1)
    6. Francese R*, Cecone C*, Costantino M, Hoti G, Bracco P, Lembo D, Trotta F. Identification of a βCD-Based Hyper-Branched Negatively Charged Polymer as HSV-2 and RSV Inhibitor. Int J Mol Sci. 2022 Aug 4;23(15):8701. doi: 10.3390/ijms23158701. PMID: 35955832; PMCID: PMC9369026 (IF: 6.208, Q1)
    7. Francese R*, Donalisio M*, Rittà M, Capitani F, Mantovani V, Maccari F, Tonetto P, Moro GE, Bertino E, Volpi N, Lembo D. Human milk glycosaminoglycans inhibit cytomegalovirus and respiratory syncytial virus infectivity by impairing cell binding. Pediatr Res. 2022 May 5. doi: 10.1038/s41390-022-02091-y. Epub ahead of print. PMID: 35513714. (IF: 3.756, Q1)
    8. Sureram S, Arduino I, Ueoka R, Rittà M, Francese R, Srivibool R, Darshana D, Piel J, Ruchirawat S, Muratori L, Lembo D, Kittakoop P, Donalisio M. The Peptide A-3302-B Isolated from a Marine Bacterium Micromonospora sp. Inhibits HSV-2 Infection by Preventing the Viral Egress from Host Cells. Int J Mol Sci. 2022 Jan 15;23(2):947. doi: 10.3390/ijms23020947. PMID: 35055133; PMCID: PMC8778767 (IF: 5.924, Q1)
    9. Balagna C, Francese R, Perero S, Lembo D, Ferraris M. Nanostructured composite coating endowed with antiviral activity against human respiratory viruses deposited on fibre-based air filters. Surf Coat Technol. 2021 Mar 15; 409:126873. doi: 10.1016/j.surfcoat.2021.126873. Epub 2021 Jan 17. PMID: 33814662; PMCID: PMC8010378. (IF: 865, Q1)
    10. Civra A*, Francese R*, Donalisio M, Tonetto P, Coscia A, Sottemano S, Balestrini R, Faccio A, Cavallarin L, Moro GE, Bertino E, Lembo D. Human Colostrum and Derived Extracellular Vesicles Prevent Infection by Human Rotavirus and Respiratory Syncytial Virus in Vitro. J Hum Lact. 2021 Feb; 37(1):122-134. doi: 10.1177/0890334420988239. Epub 2021 Feb 3. PMID: 33534629. (*Civra and Francese: co-first authors) (IF: 665, Q1)
    11. Acquadro S, Civra A, Cagliero C, Marengo A, Rittà M, Francese R, Sanna C, Bertea C, Sgorbini B, Lembo D, Donalisio M, Rubiolo P. Punica granatum Leaf Ethanolic Extract and Ellagic Acid as Inhibitors of Zika Virus Infection. Planta Med. 2020 Dec; 86(18):1363-1374. doi: 10.1055/a-1232-5705. Epub 2020 Sep 16. PMID: 32937663. (IF: 3.356, Q1)
    12. Francese R, Civra A, Donalisio M, Volpi N, Capitani F, Sottemano S, Tonetto P, Coscia A, Maiocco G, Moro GE, Bertino E, Lembo D. Anti-Zika virus and anti-Usutu virus activity of human milk and its components. PLoS Negl Trop Dis. 2020 Oct 7; 14(10):e0008713. doi: 10.1371/journal.pntd.0008713. PMID: 33027261; PMCID: PMC7571670. (IF: 4.411, Q1)
    13. Donalisio M, Cirrincione S, Rittà M, Lamberti C, Civra A, Francese R, Tonetto P, Sottemano S, Manfredi M, Lorenzato A, Moro GE, Giribaldi M, Cavallarin L, Giuffrida MG, Bertino E, Coscia A, Lembo D. Extracellular vesicles in human preterm colostrum inhibit infection by human cytomegalovirus in vitro. Microorganisms. 2020 Jul 21;8(7):1087. doi: 10.3390/microorganisms8071087. PMID: 32708203; PMCID: PMC7409124. (IF: 4.128, Q2)
    14. Civra A, Colzani M, Cagno V, Francese R, Leoni V, Aldini G, Lembo D, Poli G. Modulation of cell proteome by 25-hydroxycholesterol and 27-hydroxycholesterol: A link between cholesterol metabolism and antiviral defense. Free Radic Biol Med. 2020 Mar; 149:30-36. doi: 10.1016/j.freeradbiomed.2019.08.031. Epub 2019 Sep 13. PMID: 31525455; PMCID: PMC7126780. (IF: 6.170, Q1)
    15. Civra A, Altomare A, Francese R, Donalisio M, Aldini G, Lembo D. Colostrum from cows immunized with a veterinary vaccine against bovine rotavirus displays enhanced in vitro anti-human rotavirus activity. J Dairy Sci. 2019 Jun; 102(6):4857-4869. doi:10.3168/jds.2018-16016. Epub 2019 Apr 10. PMID:30981494 (IF 3.333, Q1)
    16. Francese R, Civra A, Rittà M, Donalisio M, Argenziano M, Cavalli R, Mougharbel AS, Kortz U, Lembo D. Anti-zika virus activity of polyoxometalates. Antiviral Res. 2019 Mar; 163:29-33. doi: 10.1016/j.antiviral.2019.01.005. Epub 2019 Jan 14. PMID:30653996 (IF 4.101, Q1)
    17. Civra A, Francese R, Gamba P, Testa G, Cagno V, Poli G, Lembo D. 25-Hydroxycholesterol and 27-hydroxycholesterol inhibit human rotavirus infection by sequestering viral particles into late endosomes. Redox Biol. 2018 Oct; 19:318-330. doi: 10.1016/j.redox.2018.09.003. Epub 2018 Sep 5. PMID: 30212801; PMCID: PMC6138790 (IF 7.793, Q1)
    18. Donalisio M, Rittà M, Francese R, Civra A, Tonetto P, Coscia A, Giribaldi M, Cavallarin L, Moro GE, Bertino E, Lembo D. High Temperature-Short Time Pasteurization Has a Lower Impact on the Antiviral Properties of Human Milk Than Holder Pasteurization. Front Pediatr. 2018 Oct 16;6:304. doi: 10.3389/fped.2018.00304. PMID: 30460212; PMCID: PMC6232822 (IF 2.349, Q2)
    19. Civra A, Francese R, Sinato D, Donalisio M, Cagno V, Rubiolo P, Ceylan R, Uysal A, Zengin G, Lembo D. In vitro screening for antiviral activity of Turkish plants revealing methanolic extract of Rindera lanata var. lanata active against human rotavirus. BMC Complement Altern Med. 2017 Jan 24; 17(1):74. doi: 10.1186/s12906-017-1560-3. PMID: 28118832; PMCID: PMC5260038 (IF: 2.109, Q2)

    Impact Factor [IF] e Quartile [Q] sono riferiti all’anno di pubblicazione secondo Journal Citation Reports; *primo nome condiviso.

    Courses

    Research topics

     

    • Ricerca e sviluppo di molecole antivirali, studio del loro meccanismo d'azione e sviluppo preclinico;
    • Studi sulle interazioni virus-cellula per approfondire le conoscenze sulla patogenesi virale e identificare nuovi bersagli farmacologici;
    • Studi antivirali nel campo dell'etnomedicina, della fitomedicina e della nutraceutica al fine di identificare composti bioattivi in piante, fonti naturali e prodotti lattiero-caseari;
    • Studi sulla trasmissione dei virus con l’allattamento e sulle proprietà antivirali del latte umano e del colostro al fine di svelare nuovi meccanismi alla base del ruolo protettivo del latte umano, e studiare l'impatto della lavorazione del latte sull'attività antivirale;
    • Ricerca di nuovi materiali antivirali per sviluppare strategie innovative volte a contrastare la diffusione di virus respiratori;
    • Studio dell’attività neutralizzante di campioni di siero umano nei confronti di virus emergenti

    Attualmente impegnata nel progetto PNRR PE13 - One Health Basic and Translational Research Actions addressing Unmet Needs on Emerging Infectious Diseases, Codice identificativo MUR: PE00000007 – CUP ENTE: D53C22002570007, SPOKE 5 - Terapie

     

    Research groups

    Research projects

    Activities in agenda

    See my calendar

    Academic bodies

    Last update: 16/04/2024 13:46
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