Department of Clinical and Biological Sciences

Research products

Selected research products

Modulation of faecal miRNAs highlights the preventive effects of a Mediterranean low-inflammatory dietary intervention
2024-01-01 Illescas, Oscar; Ferrero, Giulio; Belfiore, Antonino; Pardini, Barbara; Tarallo, Sonia; Ciniselli, Chiara M.; Noci, Sara; Daveri, Elena; Signoroni, Stefano; Cattaneo, Laura; Mancini, Andrea; Morelli, Daniele; Milione, Massimo; Cordero, Francesca; Rivoltini, Licia; Verderio, Paolo; Pasanisi, Patrizia; Vitellaro, Marco; Naccarati, Alessio; Gariboldi, Manuela https://iris.unito.it/handle/2318/1958970

Small noncoding RNAs and sperm nuclear basic proteins reflect the environmental impact on germ cells
2024-01-01 Ferrero, Giulio; Festa, Rosaria; Follia, Laura; Lettieri, Gennaro; Tarallo, Sonia; Notari, Tiziana; Giarra, Antonella; Marinaro, Carmela; Pardini, Barbara; Marano, Alessandra; Piaggeschi, Giulia; Di Battista, Carla; Trifuoggi, Marco; Piscopo, Marina; Montano, Luigi; Naccarati, Alessio https://iris.unito.it/handle/2318/1952630

A partial epithelial-mesenchymal transition signature for highly aggressive colorectal cancer cells that survive under nutrient restriction
2024-01-01 Pastorino, Gil A; Sheraj, Ilir; Huebner, Kerstin; Ferrero, Giulio; Kunze, Philipp; Hartmann, Arndt; Hampel, Chuanpit; Husnugil, Hepsen Hazal; Maiuthed, Arnatchai; Gebhart, Florian; Schlattmann, Fynn; Gulec Taskiran, Aliye Ezgi; Oral, Goksu; Palmisano, Ralph; Pardini, Barbara; Naccarati, Alessio; Erlenbach-Wuensch, Katharina; Banerjee, Sreeparna; Schneider-Stock, Regine https://iris.unito.it/handle/2318/1952430

Tamoxifen Activates Transcription Factor EB and Triggers Protective Autophagy in Breast Cancer Cells by Inducing Lysosomal Calcium Release: A Gateway to the Onset of Endocrine Resistance
2024-01-01 Boretto, Cecilia; Actis, Chiara; Faris, Pawan; Cordero, Francesca; Beccuti, Marco; Ferrero, Giulio; Muzio, Giuliana; Moccia, Francesco; Autelli, Riccardo https://iris.unito.it/handle/2318/1949895

Effect of traditional or heat‐not‐burn cigarette smoking on circulating miRNAs in healthy subjects
2023-01-01 Picchio, Vittorio; Ferrero, Giulio; Cozzolino, Claudia; Pardini, Barbara; Floris, Erica; Tarallo, Sonia; Dhori, Xhulio; Nocella, Cristina; Loffredo, Lorenzo; Biondi‐Zoccai, Giuseppe; Carnevale, Roberto; Frati, Giacomo; Chimenti, Isotta; Pagano, Francesca https://iris.unito.it/handle/2318/1946120

Profiling small RNAs in fecal immunochemical tests: is it possible?
2023-01-01 Birkeland, Einar; Ferrero, Giulio; Pardini, Barbara; Umu, Sinan U.; Tarallo, Sonia; Bulfamante, Sara; Hoff, Geir; Senore, Carlo; Rounge, Trine B; Naccarati, Alessio https://iris.unito.it/handle/2318/1935670

A fecal miRNA signature by small RNA sequencing accurately distinguishes colorectal cancers: results from a multicentric study
2023-01-01 Pardini, Barbara; Ferrero, Giulio; Tarallo, Sonia; Gallo, Gaetano; Francavilla, Antonio; Licheri, Nicola; Trompetto, Mario; Clerico, Giuseppe; Senore, Carlo; Peyre, Sergio; Vymetalkova, Veronika; Vodickova, Ludmila; Liska, Vaclav; Vycital, Ondrej; Levy, Miroslav; Macinga, Peter; Hucl, Tomas; Budinska, Eva; Vodicka, Pavel; Cordero, Francesca; Naccarati, Alessio https://iris.unito.it/handle/2318/1913511

Gluten-free diet affects fecal small non-coding RNA profiles and microbiome composition in celiac disease supporting a host-gut microbiota crosstalk
2023-01-01 Francavilla, Antonio; Ferrero, Giulio; Pardini, Barbara; Tarallo, Sonia; Zanatto, Laura; Caviglia, Gian Paolo; Sieri, Sabina; Grioni, Sara; Francescato, Giulia; Stalla, Francesco; Guiotto, Cristina; Crocella, Lucia; Astegiano, Marco; Bruno, Mauro; Calvo, Pier Luigi; Vineis, Paolo; Ribaldone, Davide Giuseppe; Naccarati, Alessio https://iris.unito.it/handle/2318/1891203

A Regulatory Axis between Epithelial Splicing Regulatory Proteins and Estrogen Receptor α Modulates the Alternative Transcriptome of Luminal Breast Cancer
2022-01-01 Elhasnaoui, Jamal; Ferrero, Giulio; Miano, Valentina; Franchitti, Lorenzo; Tarulli, Isabella; Coscujuela Tarrero, Lucia; Cutrupi, Santina; De Bortoli, Michele https://iris.unito.it/handle/2318/1870401

Integrative genomic and transcriptomic analyses illuminate the ontology of HER2-low breast carcinomas
2022-01-01 Berrino, Enrico; Annaratone, Laura; Bellomo, Sara Erika; Ferrero, Giulio; Gagliardi, Amedeo; Bragoni, Alberto; Grassini, Dora; Guarrera, Simonetta; Parlato, Caterina; Casorzo, Laura; Panero, Mara; Sarotto, Ivana; Giordano, Silvia; Cereda, Matteo; Montemurro, Filippo; Ponzone, Riccardo; Crosetto, Nicola; Naccarati, Alessio; Sapino, Anna; Marchiò, Caterina https://iris.unito.it/handle/2318/1875621

The 8q24 region hosts miRNAs altered in biospecimens of colorectal and bladder cancer patients
2022-01-01 Gagliardi, Amedeo; Francescato, Giulia; Ferrero, Giulio; Birolo, Giovanni; Tarallo, Sonia; Francavilla, Antonio; Piaggeschi, Giulia; Di Battista, Carla; Gallo, Gaetano; Realis Luc, Alberto; Sacerdote, Carlotta; Matullo, Giuseppe; Vineis, Paolo; Naccarati, Alessio; Pardini, Barbara https://iris.unito.it/handle/2318/1879540

Combined miRNA and SERS urine liquid biopsy for the point-of-care diagnosis and molecular stratification of bladder cancer
2022-01-01 Moisoiu T.; Dragomir M.P.; Iancu S.D.; Schallenberg S.; Birolo G.; Ferrero G.; Burghelea D.; Stefancu A.; Cozan R.G.; Licarete E.; Allione A.; Matullo G.; Iacob G.; Balint Z.; Badea R.I.; Naccarati A.; Horst D.; Pardini B.; Leopold N.; Elec F. https://iris.unito.it/handle/2318/1858345

DNA damage response and repair genes in advanced bone and soft tissue sarcomas: An 8-gene signature as a candidate predictive biomarker of response to trabectedin and olaparib combination
2022-01-01 Alessandra Merlini, Maria Laura Centomo, Giulio Ferrero, Giulia Chiabotto, Umberto Miglio,Enrico Berrino, Giorgia Giordano, Silvia Brusco, Alberto Pisacane, Elena Maldi, Ivana Sarotto,Federica Capozzi, Cristina Lano, Claudio Isella, Giovanni Crisafulli, Massimo Aglietta,Angelo Paolo Dei Tos, Marta Sbaraglia,Dario Sangiolo, Lorenzo D’Ambrosio, Alberto Bardelli, Ymera Pignochino, Giovanni Grignani https://iris.unito.it/handle/2318/1875243

Computational Analysis of circRNA Expression Data
2021-01-01 Ferrero G.; Licheri N.; De Bortoli M.; Calogero R.A.; Beccuti M.; Cordero F. https://iris.unito.it/handle/2318/1797838

The estrogen receptor α signaling pathway controls alternative splicing in the absence of ligands in breast cancer cells
2021-01-01 Elhasnaoui J.; Ferrero G.; Miano V.; Cutrupi S.; De Bortoli M. https://iris.unito.it/handle/2318/1826498

Stool microRNA profiles reflect different dietary and gut microbiome patterns in healthy individuals
2021-01-01 Tarallo S.; Ferrero G.; De Filippis F.; Francavilla A.; Pasolli E.; Panero V.; Cordero F.; Segata N.; Grioni S.; Pensa R.G.; Pardini B.; Ercolini D.; Naccarati A. https://iris.unito.it/handle/2318/1803308

Intake of Natural Compounds and Circulating microRNA Expression Levels: Their Relationship Investigated in Healthy Subjects With Different Dietary Habits
2021-01-01 Ferrero, Giulio; Carpi, Sara; Polini, Beatrice; Pardini, Barbara; Nieri, Paola; Impeduglia, Alessia; Grioni, Sara; Tarallo, Sonia; Naccarati, Alessio https://iris.unito.it/handle/2318/1766877

Faecal miRNA profiles associated with age, sex, BMI, and lifestyle habits in healthy individuals
2021-01-01 Francavilla, Antonio; Gagliardi, Amedeo; Piaggeschi, Giulia; Tarallo, Sonia; Cordero, Francesca; Pensa, Ruggero G.; Impeduglia, Alessia; Caviglia, Gian Paolo; Ribaldone, Davide Giuseppe; Gallo, Gaetano; Grioni, Sara; Ferrero, Giulio; Pardini, Barbara; Naccarati, Alessio https://iris.unito.it/handle/2318/1813124

Epha2 expression in bone sarcomas: Bioinformatic analyses and preclinical characterization in patient-derived models of osteosarcoma, ewing’s sarcoma and chondrosarcoma
2021-01-01 Giordano G.; Merlini A.; Ferrero G.; Mesiano G.; Fiorino E.; Brusco S.; Centomo M.L.; Leuci V.; D'ambrosio L.; Aglietta M.; Sangiolo D.; Grignani G.; Pignochino Y. https://iris.unito.it/handle/2318/1835642

In pancreatic cancer chemotherapy increases anti-tumor responses to tumor associated antigens and potentiates DNA vaccination
2020-01-01 Mandili G, Curcio C, Bulfamante S, Follia L, Ferrero G, Mazza E, Principe M, Cordero F, Satolli MA, Spadi R, Evangelista A, Giordano D, Viet D, Cappello P, Novelli F. https://iris.unito.it/handle/2318/1763253

Immune-Complexome Analysis Identifies Immunoglobulin-Bound Biomarkers That Predict the Response to Chemotherapy of Pancreatic Cancer Patients
2020-01-01 Giorgia Mandili, Laura Follia , Giulio Ferrero , Hiroyuki Katayama, Wang Hong 5, Amin A. Momin , Michela Capello , Daniele Giordano, Rosella Spadi, Maria Antonietta Satolli , Andrea Evangelista , Samir M. Hanash , Francesca Cordero, Francesco Novelli https://iris.unito.it/handle/2318/1734243

Docker4Circ: A Framework for the Reproducible Characterization of circRNAs from RNA-Seq Data
2020-01-01 Ferrero, Giulio; Licheri, Nicola; Coscujuela Tarrero, Lucia; De Intinis, Carlo; Miano, Valentina; Calogero, Raffaele Adolfo; Cordero, Francesca; De Bortoli, Michele; Beccuti, Marco https://iris.unito.it/handle/2318/1723109

Small nucleolar RNAs determine resistance to doxorubicin in human osteosarcoma
2020-01-01 Godel M.; Morena D.; Ananthanarayanan P.; Buondonno I.; Ferrero G.; Hattinger C.M.; Di Nicolantonio F.; Serra M.; Taulli R.; Cordero F.; Riganti C.; Kopecka J. https://iris.unito.it/handle/2318/1747161

DSCAM-AS1-Driven Proliferation of Breast Cancer Cells Involves Regulation of Alternative Exon Splicing and 3′-End Usage
2020-01-01 Elhasnaoui, Jamal; Miano, Valentina; Ferrero, Giulio; Doria, Elena; Leon, Antonette E.; Fabricio, Aline S. C.; Annaratone, Laura; Castellano, Isabella; Sapino, Anna; De Bortoli, Michele https://iris.unito.it/handle/2318/1740553

Pregnancy epigenetic signature in T helper 17 and T regulatory cells in multiple sclerosis
2019-01-01 Andrea Iannello, Simona Rolla, Alessandro Maglione, Giulio Ferrero, Valentina Bardina, Ilenia Inaudi, Stefania De Mercanti, Francesco Novelli, Lucrezia D'Antuono, Simona Cardaropoli, Tullia Todros, Maria Vittoria Turrini, Cinzia Cordioli, Giorgia Puorro, Angela Marsili, Roberta Lanzillo, Vincenzo Brescia Morra, Francesca Cordero, Michele De Bortoli, Luca Durelli, Andrea Visconti, Santina Cutrupi, Marinella Clerico https://iris.unito.it/handle/2318/1690070

MethylFASTQ: A Tool Simulating Bisulfite Sequencing Data
2019-01-01 Piaggeschi, Giulia; Licheri, Nicola; Romano, Greta; Pernice, Simone; Follia, Laura; Ferrero, Giulio https://iris.unito.it/handle/2318/1695383

Integrative Analysis of Novel Metabolic Subtypes in Pancreatic Cancer Fosters New Prognostic Biomarkers
2019-01-01 Follia, Laura; Ferrero, Giulio; Mandili, Giorgia; Beccuti, Marco; Giordano, Daniele; Spadi, Rosella; Satolli, Maria Antonietta; Evangelista, Andrea; Katayama, Hiroyuki; Hong, Wang; Momin, Amin A.; Capello, Michela; Hanash, Samir M.; Novelli, Francesco; Cordero, Francesca https://iris.unito.it/handle/2318/1694079

Altered Fecal Small RNA Profiles in Colorectal Cancer Reflect Gut Microbiome Composition in Stool Samples
2019-01-01 Tarallo, Sonia; Ferrero, Giulio; Gallo, Gaetano; Francavilla, Antonio; Clerico, Giuseppe; Realis Luc, Alberto; Manghi, Paolo; Thomas, Andrew Maltez; Vineis, Paolo; Segata, Nicola; Pardini, Barbara; Naccarati, Alessio; Cordero, Francesca https://iris.unito.it/handle/2318/1712121

Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation
2019-01-01 Thomas, Andrew Maltez; Manghi, Paolo; Asnicar, Francesco; Pasolli, Edoardo; Armanini, Federica; Zolfo, Moreno; Beghini, Francesco; Manara, Serena; Karcher, Nicolai; Pozzi, Chiara; Gandini, Sara; Serrano, Davide; Tarallo, Sonia; Francavilla, Antonio; Gallo, Gaetano; Trompetto, Mario; Ferrero, Giulio; Mizutani, Sayaka; Shiroma, Hirotsugu; Shiba, Satoshi; Shibata, Tatsuhiro; Yachida, Shinichi; Yamada, Takuji; Wirbel, Jakob; Schrotz-King, Petra; Ulrich, Cornelia M; Brenner, Hermann; Arumugam, Manimozhiyan; Bork, Peer; Zeller, Georg; Cordero, Francesca; Dias-Neto, Emmanuel; Setubal, João Carlos; Tett, Adrian; Pardini, Barbara; Rescigno, Maria; Waldron, Levi; Naccarati, Alessio; Segata, Nicola https://iris.unito.it/handle/2318/1696662

THE EXPRESSION OF LINE1-MET CHIMERIC TRANSCRIPT IDENTIFIES A SUBGROUP OF AGGRESSIVE BREAST CANCERS
2018-01-01 Umberto Miglio, Enrico Berrino, Mara Panero, Giulio Ferrero, Lucia Coscujuela Tarrero, Valentina Miano, Carmine Dell'Aglio, Ivana Sarotto, Laura Annaratone, Caterina Marchiò, Paolo M. Comoglio, Michele De Bortoli, Barbara Pasini, Tiziana Venesio, Anna Sapino https://iris.unito.it/handle/2318/1677559

Chemotherapy effects on immune-complexes in pancreatic ductal adenocarcinoma patients serum
2018-01-01 Giorgia Mandili, Laura Follia, Giulio Ferrero, Hiroyuki Katayama, Wang Hong, Amin A. Momin, Michela Capello, Francesca Cordero, Samir M. Hanash, Francesco Novelli https://iris.unito.it/handle/2318/1679174

An integrative transcriptomic analysis of glycolytic genes reveals distinct metabolic subtypes in pancreatic cancer
2018-01-01 Laura Follia, Giulio Ferrero, Giorgia Mandili, Marco Beccuti, Hiroyuki Katayama, Hong Wang, Amin A. Momin, Michela Capello, Samir M. Hanash, Francesco Novelli, Francesca Cordero https://iris.unito.it/handle/2318/1679187

Luminal breast cancer-specific circular RNAs uncovered by a novel tool for data analysis
2018-01-01 Tarrero, Lucia Coscujuela; Ferrero, Giulio; Miano, Valentina; De Intinis, Carlo; Ricci, Laura; Arigoni, Maddalena; Riccardo, Federica; Annaratone, Laura; Castellano, Isabella; Calogero, Raffaele A.; Beccuti, Marco; Cordero, Francesca; De Bortoli, Michele https://iris.unito.it/handle/2318/1662333

Integrative analysis of -omics data reveals estrogen-responsive regions in Th17 and Treg genomes
2018-01-01 Maglione A , Ferrero G, Iannello A, Cordero F, Clerico M, Cutrupi S https://iris.unito.it/handle/2318/1758373

Reproducible bioinformatics project: A community for reproducible bioinformatics analysis pipelines
2018-01-01 Neha Kulkarni, Luca Alessandrì, Riccardo Panero, Maddalena Arigoni, Martina Olivero, Giulio Ferrero, Francesca Cordero, Marco Beccuti, Raffaele A. Calogero https://iris.unito.it/handle/2318/1678312

Luminal lncRNAs Regulation by ERα-Controlled Enhancers in a Ligand-Independent Manner in Breast Cancer Cells
2018-01-01 Valentina Miano, Giulio Ferrero, Valentina Rosti, Eleonora Manitta, Jamal Elhasnaoui, Giulia Basile, Michele De Bortoli https://iris.unito.it/handle/2318/1660603

Epigenetic signature in T helper 17 and regulatory T cells in multiple sclerosis patients during pregnancy
2018-01-01 Andrea Iannello, Alessandro Maglione, Giulio Ferrero, Simona Rolla, Valentina Bardina, Francesca Cordero, Michele De Bortoli, Marinella Clerico, Santina Cutrupi https://iris.unito.it/handle/2318/1758374

Small non-coding RNA profiling in human biofluids and surrogate tissues from healthy individuals: Description of the diverse and most represented species
2018-01-01 Ferrero, Giulio; Cordero, Francesca; Tarallo, Sonia; Arigoni, Maddalena; Riccardo, Federica; Gallo, Gaetano; Ronco, Guglielmo; Allasia, Marco; Kulkarni, Neha; Matullo, Giuseppe; Vineis, Paolo; Calogero, Raffaele A.; Pardini, Barbara; Naccarati, Alessio https://iris.unito.it/handle/2318/1659484

Antibody and T cell response profiling in pancreatic cancer patients before and after chemotherapy identify tumor associated antigens suitable for immunotherapy
2018-01-01 Sara Bulfamante, Giorgia Mandili, Moitza Principe, Daniele Giordano, Emanuela Mazza, Claudia Curcio, Laura Follia, Giulio Ferrero, Andrea Evangelista, Maria Antonietta Satolli, Paola Cappello, Francesco Novelli https://iris.unito.it/handle/2318/1679081

ParallNormal: An Efficient Variant Calling Pipeline for Unmatched Sequencing Data
2018-01-01 Laura Follia, Fabio Tordini, Simone Pernice, https://iris.unito.it/handle/2318/1669999

Dissecting the genomic activity of a transcriptional regulator by the integrative analysis of omics data
2017-01-01 Ferrero, Giulio; Miano, Valentina; Beccuti, Marco; Balbo, Gianfranco; De Bortoli, Michele; Cordero, Francesca https://iris.unito.it/handle/2318/1647614

Chromatin remodeling in Th17 and Treg plasticity induced by E2 immunomodulation
2017-01-01 Iannello A., Ferrero G., Maglione A., Cordero F., Rolla S., Bardina V., De Mercanti S., Durelli L., Clerico M., Cutrupi S. https://iris.unito.it/handle/2318/1758375

Biologic Data of Cynomolgus Monkeys Maintained under Laboratory Conditions
2016-01-01 Rosso, MARILENA CATERINA; Badino, Paola; Ferrero, Giulio; Costa, Roberto; Cordero, Francesca; Steidler, Stephanie https://iris.unito.it/handle/2318/1576376

Luminal long non-coding RNAs regulated by estrogen receptor alpha in a ligand-independent manner show functional roles in breast cancer
2016-01-01 Miano, Valentina; Ferrero, Giulio; Reineri, Stefania; Caizzi, Livia; Annaratone, Laura; Ricci, Laura; Cutrupi, Santina; Castellano, Isabella; Cordero, Francesca; De Bortoli, Michele https://iris.unito.it/handle/2318/1531412

E2 regulates epigenetic signature on neuroglobin enhancer-promoter in neuronal cells
2016-01-01 Guglielmotto, Michela; Reineri, Stefania; Iannello, Andrea; Ferrero, Giulio; Vanzan, Ludovica; Miano, Valentina; Ricci, Laura; Tamagno, Elena; De Bortoli, Michele; Cutrupi, Santina https://iris.unito.it/handle/2318/1576752

Differentially methylated microRNAs in prediagnostic samples of subjects who developed breast cancer in the european prospective investigation into nutrition and cancer (EPIC-Italy) cohort
2015-01-01 Cordero, Francesca; Ferrero, Giulio; Polidoro, Silvia; Fiorito, Giovanni; Campanella, Gianluca; Sacerdote, Carlotta; Mattiello, Amalia; Masala, Giovanna; Agnoli, Claudia; Frasca, Graziella; Panico, Salvatore; Palli, Domenico; Krogh, Vittorio; Tumino, Rosario; Vineis, Paolo; Naccarati, Alessio https://iris.unito.it/handle/2318/1532163

Genome-wide activity of unliganded estrogen receptor-α  in breast cancer cells
2014-01-01 L. Caizzi;G. Ferrero;S. Cutrupi;F. Cordero;C. Ballare;V. Miano;S. Reineri;L. Ricci;O. Friard;A. Testori;D. Cora;M. Caselle;L. Di Croce;M. De Bortoli https://iris.unito.it/handle/2318/143016

Sequence Alignment Tools: One Parallel Pattern to Rule Them All?
2014-01-01 Claudia Misale;Giulio Ferrero;Massimo Torquati;Marco Aldinucci https://iris.unito.it/handle/2318/147826

Genomic lens on neuroglobin transcription.
2014-01-01 Cutrupi S;Ferrero G;Reineri S;Cordero F;De Bortoli M https://iris.unito.it/handle/2318/147592

Courses

• ADVANCED MOLECULAR BIOLOGY (Biomedical) (SVB0041)
  Cellular and Molecular Biology
• Biochemical and Molecular Basis of Metabolism (SCB0314)
  MedInTO Medicine and Surgery
• Biochemical and Molecular Basis of Metabolism - Module of Bioinformatics (SCB0314D)
  MedInTO Medicine and Surgery
• FISICA E INFORMATICA (BIO0222)
  Corso di Laurea in Biotecnologie
• Informatica (BIO0222B)
  Corso di Laurea in Biotecnologie

Research topics

Research groups

• Genomic Regulation Group

Research projects

• Identificazione di biomarcatori fecali di esposizione cronica ad inquinanti ambientali
• Regolazione trascrizionale e post-trascrizionale da parte del recettore alfa degli estrogeni
• RNA circolari come biomarcatori precoci del carcinoma polmonare: un approccio di biopsia liquida
• Studio degli effetti biologici a livello genomico ed epigenomico dell’esposizione a contaminanti ambientali per la definizione di classificatori di rischio

Activities in agenda

See my calendar

Academic bodies

• Consiglio di Dipartimento - Dipartimento di Scienze Cliniche e Biologiche